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K. B. Mullis' inspiration for PCR (May 1983) at milepost 46.58 - Sep 2010

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Comments (3)

MaxFarrar on January 2, 2011

From Wikipedia: The polymerase chain reaction (PCR) is a scientific technique in molecular biology to amplify a single or a few copies of a piece of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.

This layby is where KB Mullis invented this process which benefits us all in May 1983.

georgefranklin on February 28, 2012

How do you know this is THE spot the he had the revelation that led to PCR? I'm from Mendocino and have worked in a genetics lab. I've always loved the story that on a trip to the mystical coast of Mendo on Hwy 128 Kerry Mullis had his Nobel inspiration that led to PCR, but did it happen Right Here?

MaxFarrar on February 28, 2012

Thank you for your comment George. I got it from the horse's mouth. I read a newspaper article a few years ago that mentioned he alway told the story about the revelation at milepost 46.58 when he gave speeches and lectures. Here's a link to his website that tells the story: I stopped to take this picture a couple years ago on the way to visit friends in Boonville.

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Photo details

  • Uploaded on September 14, 2010
  • © All Rights Reserved
    by MaxFarrar
    • Camera: NIKON COOLPIX P5100
    • Taken on 2010/09/06 11:17:47
    • Exposure: 0.001s
    • Focal Length: 7.50mm
    • F/Stop: f/3.800
    • ISO Speed: ISO64
    • Exposure Bias: -0.30 EV
    • No flash